1,2,3-Triazolium macrocycles in supramolecular chemistry

• Mastaneh Safarnejad Shad,
• Pulikkal Veettil Santhini and
• Wim Dehaen

Beilstein J. Org. Chem. 2019, 15, 2142–2155, doi:10.3762/bjoc.15.211

• highly functionalized 1,2,3-triazolium macrocycles under optimized reaction conditions, although cyclizations also have been carried out starting from triazolium building blocks (Figure 2). Using a small variation in the reaction protocols of the click reaction, iodine atoms can be introduced at the 5

• in the literature in which they bind to the anionic species by utilizing multiple noncovalent interactions based on electrostatics, including hydrogen bonding (HB), anion–π interactions [30], and on Lewis acidity/basicity [31]. 2.1. Bile acid-based 1,2,3-triazolium macrocycles Bile acid-based

• selectivity of this receptor for chloride anion is due to the cavity size (see Figure 3) [37]. 2.2. Optical anion sensing by 1,2,3-triazolium macrocycles within porphyrin cages Various porphyrin-based host supramolecules containing hydrogen-bond donor groups such as integrated amide, urea, pyrrole, ammonium